{"id":45,"date":"2008-03-28T14:36:29","date_gmt":"2008-03-28T14:36:29","guid":{"rendered":"http:\/\/jha.in\/?p=52"},"modified":"2008-03-28T14:36:29","modified_gmt":"2008-03-28T14:36:29","slug":"rectal-artemisin-derivative-for-initial-control-of-malaria","status":"publish","type":"post","link":"https:\/\/jha.in\/?p=45","title":{"rendered":"Rectal artemisin derivative for initial control of malaria"},"content":{"rendered":"<p>There is this interesting article in todays <a href=\"http:\/\/www.biomedcentral.com\/bmcinfectdis\/\">BMC Infectious disease<\/a> which had my attention. the featured article says<\/p>\n<blockquote>\n<p><b>Rectal artemisinins rapidly reduce malaria <i>viral <\/i>load<\/b><br \/>BMC Infectious Diseases 2008, 8:39<\/p>\n<p>Artemisinins administered as rectal suppositories, particularly artesunate as a single high dose, reduce malaria parasite load within 24 hours without serious adverse effects, offering an alternative to intravenous quinine therapy in remote areas where trained personnel are scarce. <\/p>\n<\/blockquote>\n<p>Don&#8217;t  laugh- but my first thoughts was HOW did they manage it technically!? on reading the whole article I realized they meant malarial parasite load in people not umm&#8230; mosquitoes. <br \/>you can read the <a href=\"http:\/\/www.biomedcentral.com\/content\/pdf\/1471-2334-8-39.pdf\">full article<\/a> here (<a href=\"http:\/\/www.biomedcentral.com\/1471-2334\/8\/39\/abstract\">open access<\/a> abstract).<\/p>\n<p>From my earlier days i remember there was increasing resistance to artemisin derivatives and I suppose combination therapy is advised to reduce those chances.I wonder how this will have impact on drug resistance in future.<\/p>\n<p>Note: It is not <i>viral<\/i>.<\/p>\n<p>&amp;ps- i will try to post regularly.<\/p>\n<\/p>\n<p class=\"poweredbyperformancing\">Powered by <a href=\"http:\/\/scribefire.com\/\">ScribeFire<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>There is this interesting article in todays BMC Infectious disease which had my attention. the featured article says Rectal artemisinins rapidly reduce malaria viral loadBMC Infectious Diseases 2008, 8:39 Artemisinins administered as rectal suppositories, particularly artesunate as a single high dose, reduce malaria parasite load within 24 hours without serious adverse effects, offering an alternative [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[6,10],"tags":[],"class_list":["post-45","post","type-post","status-publish","format-standard","hentry","category-humor","category-medicine","entry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Rectal artemisin derivative for initial control of malaria<\/title>\n<meta name=\"description\" content=\"Rectal artemisin 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